Description

4-[4-Nitro-2-(Trifluoromethyl)Phenoxy]Benzenesulfonyl Chloride is a high-value, multi-functional chemical intermediate characterized by its sulfonyl chloride and aromatic nitro-trifluoromethyl motifs. This compound matters for its critical role in the synthesis of advanced molecules, offering a reactive handle for constructing sulfonamides and other complex structures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, including potential enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides leveraging the bioactivity of the sulfonamide functional group.
• Material Science Research: Serves as a precursor for creating specialized polymers or surface-modifying agents with unique properties.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes for studying enzyme function and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom chemical synthesis services catering to advanced R&D projects.

Basic Information

Product Name	4-[4-Nitro-2-(Trifluoromethyl)Phenoxy]Benzenesulfonyl Chloride
CAS No.	1858255-92-1
Molecular Formula	C₁₃H₇ClF₃NO₅S
Molecular Weight	381.71 g/mol
Synonyms	4-(4-Nitro-2-(trifluoromethyl)phenoxy)benzenesulfonyl chloride; 1-Chlorosulfonyl-4-[4-nitro-2-(trifluoromethyl)phenoxy]benzene; Benzenesulfonyl chloride, 4-[4-nitro-2-(trifluoromethyl)phenoxy]-; 4-Nitro-2-trifluoromethylphenyl 4-chlorosulfonylphenyl ether
EINECS	Contact for details

Quality Control

Our production of 4-[4-Nitro-2-(Trifluoromethyl)Phenoxy]Benzenesulfonyl Chloride adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.