Description

Mal-Peg-Fitc CAS NO 1845706-65-1 is a high-purity, bifunctional fluorescent labeling reagent designed for advanced bioconjugation and biomolecular research. This compound is critical for creating stable, traceable conjugates due to its maleimide group for thiol-specific coupling, polyethylene glycol (PEG) spacer for enhanced solubility and reduced immunogenicity, and the FITC fluorophore for high-sensitivity detection. It is an essential tool for researchers and developers in pharmaceutical R&D, diagnostic assay development, and advanced materials science who require precise and reliable fluorescent tagging of proteins, antibodies, and nanoparticles.

Application

• Antibody-Drug Conjugate (ADC) Development: Site-specific conjugation of cytotoxic drugs or reporter molecules to antibodies via engineered cysteine residues.
• Protein Labeling & Tracking: Fluorescent tagging of thiol-containing proteins for studies in cellular uptake, localization, and protein-protein interactions.
• Diagnostic Probe Synthesis: Manufacturing fluorescent probes and biosensors for immunoassays (e.g., ELISA, flow cytometry) and in vitro diagnostics.
• Nanoparticle Functionalization: Surface modification of gold nanoparticles, liposomes, or polymeric micelles to create targeted, traceable drug delivery systems.
• Peptide Chemistry: Conjugation to cysteine-containing peptides for creating fluorescent peptide substrates or probes.
• Biomaterial Research: Incorporation into hydrogels or polymer scaffolds to visualize material integration and cell interactions.

Basic Information

Product Name	Mal-Peg-Fitc
CAS No.	1845706-65-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Maleimide-PEG-FITC; MAL-PEG-Fluorescein Isothiocyanate; FITC-PEG-Maleimide; 5-FITC-PEG-MAL; Fluorescein-PEG-Maleimide; N-(Fluorescein-5-thiocarbamoyl)-PEG-Maleimide; PEG-FITC-Maleimide; Maleimide Polyethylene Glycol Fluorescein Isothiocyanate
EINECS	Contact for details

Quality Control

Our Mal-Peg-Fitc is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and substitution ratio analysis, NMR for structural confirmation, and spectrophotometry for fluorophore quantification. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research and development specifications. Our quality system supports applications requiring high consistency and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake. For long-term storage, keep under an inert atmosphere.

Specification

Item	Specification
Appearance	Orange to red solid or powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Maleimide Substitution	≥ 90%
FITC Content	As per COA
PEG Molecular Weight	e.g., 2000 Da, 3400 Da, 5000 Da (Customizable)
Solubility	Soluble in DMSO, DMF, water (PEG dependent)
Moisture Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.