Description

Pi3Kβ And δ Inhibitor 20A is a potent and selective small molecule inhibitor targeting specific isoforms of the phosphoinositide 3-kinase (PI3K) family. This compound is a critical research tool for elucidating the distinct roles of PI3Kβ and PI3Kδ signaling pathways in cellular processes and disease models. It is primarily utilized by pharmaceutical R&D teams and academic researchers focused on oncology, immunology, and metabolic disorders. The product, identified by CAS No. 1842380-77-1, is supplied to the highest standards to ensure reliable and reproducible experimental results.

Application

• Biochemical Research: Used as a selective probe to study the specific functions of PI3Kβ and PI3Kδ isoforms in signal transduction pathways.
• Oncology Research: Investigated for its potential to inhibit cancer cell proliferation, survival, and metastasis in preclinical models, particularly in hematological malignancies and solid tumors driven by PI3K signaling.
• Immunology & Inflammation Studies: Applied in research to understand the role of PI3Kδ in immune cell activation, with implications for autoimmune and inflammatory diseases.
• Drug Discovery & Development: Serves as a reference compound or a starting point for the design and optimization of novel therapeutic agents targeting the PI3K pathway.
• Cellular Mechanism Studies: Employed in cell-based assays to dissect the contribution of PI3Kβ/δ to cellular responses like growth, metabolism, and migration.
• Target Validation: Used in genetic and pharmacological studies to validate PI3Kβ and PI3Kδ as viable therapeutic targets for various diseases.

Basic Information

Product Name	Pi3Kβ And δ Inhibitor 20A
CAS No.	1842380-77-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	PI3Kβ/δ Inhibitor 20A; PI3K Beta Delta Inhibitor 20A; 20A PI3K Inhibitor; Compound 20A; PI3Kβδ Inhibitor; Research Compound 1842380-77-1; Selective PI3Kβ and PI3Kδ Inhibitor
EINECS	Contact for details

Quality Control

Our Pi3Kβ And δ Inhibitor 20A is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including purity verification by HPLC and structural confirmation. A Certificate of Analysis (COA) detailing identity, purity, and quality specifications is provided with every shipment to support your research integrity and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at recommended temperatures (typically 2-8°C or as specified on the label). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.