Description

3-(Trifluoromethyl)Quinoline-5-Carboxylic Acid is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique molecular architecture, featuring both a quinoline core and a trifluoromethyl group, makes it a critical intermediate for developing novel compounds with enhanced properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and anti-infective research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl group can improve metabolic stability and bioavailability.
• Material Science: Serves as a precursor for functional organic materials, including ligands for catalysis and components for organic light-emitting diodes (OLEDs).
• Chemical Research: A versatile scaffold in medicinal and combinatorial chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fluorine Chemistry: Valuable for introducing the trifluoromethyl moiety into complex molecules, a common strategy in modern drug design.

Basic Information

Product Name	3-(Trifluoromethyl)Quinoline-5-Carboxylic Acid
CAS No.	1841081-82-0
Molecular Formula	C11H6F3NO2
Molecular Weight	241.17 g/mol
Synonyms	5-Quinolinecarboxylic acid, 3-(trifluoromethyl)-; 3-Trifluoromethylquinoline-5-carboxylic acid; 3-(Trifluoromethyl)-5-quinolinecarboxylic acid; Quinoline-5-carboxylic acid, 3-(trifluoromethyl)-; 1841081-82-0; 3-TFMQ-5-COOH
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Quinoline-5-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee it meets your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.