Description

Endosidin 2 is a potent and selective small-molecule inhibitor of endocytosis, specifically targeting the clathrin-mediated pathway. This compound is a critical research tool for studying intracellular trafficking, membrane dynamics, and plant cell biology. It is primarily utilized by researchers in academic, biotechnology, and pharmaceutical sectors for fundamental cell biology studies and drug discovery programs.

Application

• Cell Biology Research: A key reagent for investigating clathrin-mediated endocytosis (CME) and intracellular vesicle trafficking in eukaryotic cells.
• Plant Science Studies: Used to study endocytosis in plant cells, providing insights into growth, development, and environmental response mechanisms.
• Drug Discovery Screening: Serves as a pharmacological tool in high-throughput screening assays to identify novel compounds affecting endocytic pathways.
• Mechanistic Studies: Enables the dissection of specific endocytic pathways to understand their role in signal transduction, nutrient uptake, and receptor regulation.
• Neuroscience Research: Applied in studies of synaptic vesicle recycling and neurotransmitter receptor internalization in neuronal models.
• Virology and Pathogen Entry: Used to probe the entry mechanisms of viruses and other pathogens that hijack host endocytic machinery.

Basic Information

Product Name	Endosidin 2
CAS No.	1839524-44-5
Molecular Formula	C₁₉H₁₈N₂O₄
Molecular Weight	338.36 g/mol
Synonyms	ES2; Endosidin2; 5-[(2,4-Dichlorophenyl)methyl]-2,4-dihydro-3H-1,2,4-triazole-3,4-dione; 5-[(2,4-Dichlorophenyl)methyl]-1H-1,2,4-triazole-3,4(2H)-dione; Endocytosis Inhibitor ES2; Clathrin Inhibitor ES2
EINECS	Contact for details

Quality Control

Our Endosidin 2 is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant standards for research-grade biochemicals to guarantee reliable and reproducible experimental results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.