Description

1-(2-Chloro-4-(Difluoromethoxy)Phenyl)Ethanone is a specialized organic intermediate featuring a unique difluoromethoxy and chloro-substituted aromatic ketone structure. This compound is of significant value in advanced organic synthesis, particularly for constructing complex molecules where its specific halogen and fluorine-containing functional groups are critical. It is primarily needed by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluoromethoxy group can enhance biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, or organic electronic materials requiring specific fluorine-based properties.
• Chemical Biology Probes: Employed in the creation of molecular probes and tags for studying biological processes and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	1-(2-Chloro-4-(Difluoromethoxy)Phenyl)Ethanone
CAS No.	1824648-23-8
Molecular Formula	C9H7ClF2O2
Molecular Weight	220.60 g/mol
Synonyms	2'-Chloro-4'-(difluoromethoxy)acetophenone; 1-[2-Chloro-4-(difluoromethoxy)phenyl]ethan-1-one; 2-Chloro-4-(difluoromethoxy)acetophenone; 1-(2-Chloro-4-(difluoromethoxyphenyl))ethanone; 1-(2-Chloro-4-(difluoromethoxy)phenyl)ethanone; 2-Chloro-α,α-difluoro-4-methoxyacetophenone; Acetophenone, 2'-chloro-4'-(difluoromethoxy)-
EINECS	Contact for details

Quality Control

Our production of 1-(2-Chloro-4-(Difluoromethoxy)Phenyl)Ethanone adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We operate under a quality system designed to meet the rigorous standards of our pharmaceutical and agrochemical partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.