Description

5-Ethynyl-6-Fluoropyridin-2-Amine is a high-value, multi-functional pyridine derivative featuring both an ethynyl and a fluorine substituent. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block for the synthesis of complex organic molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the creation of novel herbicides and pesticides, leveraging its unique halogenated pyridine core.
• Ligand & Catalyst Development: The ethynyl group allows for facile functionalization via click chemistry, making it valuable for creating specialized ligands and catalysts.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probe: Utilized in bioconjugation and labeling strategies to study biological systems due to its reactive alkyne handle.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up manufacturing for clinical trials.

Basic Information

Product Name	5-Ethynyl-6-Fluoropyridin-2-Amine
CAS No.	1824299-95-7
Molecular Formula	C7H5FN2
Molecular Weight	136.13 g/mol
Synonyms	2-Amino-5-ethynyl-6-fluoropyridine; 6-Fluoro-5-ethynylpyridin-2-amine; 5-Ethynyl-6-fluoro-2-pyridinamine; 5-Ethynyl-6-fluoro-2-aminopyridine; 2-Pyridinamine, 5-ethynyl-6-fluoro-; 1824299-95-7; FCAS 1824299-95-7
EINECS	Contact for details

Quality Control

Our 5-Ethynyl-6-Fluoropyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.