Description

3-Fluoroquinoline-6-Carboxylic Acid is a high-purity fluorinated quinoline derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular structure, which introduces both a carboxylic acid handle and a fluorine atom onto the quinoline scaffold, enabling precise modifications in target molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in kinase inhibitor and antimicrobial programs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the fluorine atom can enhance bioavailability and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for constructing complex chelating ligands used in catalysis and material science.
• Fluorescent Probe and Dye Chemistry: The quinoline core makes it suitable for developing new fluorophores and sensing materials.
• Academic and Contract Research: Employed in university and CRO laboratories for methodological studies and the synthesis of complex heterocyclic libraries.

Basic Information

Product Name	3-Fluoroquinoline-6-Carboxylic Acid
CAS No.	1824275-93-5
Molecular Formula	C10H6FNO2
Molecular Weight	191.16 g/mol
Synonyms	6-Quinolinecarboxylic acid, 3-fluoro-; 3-Fluoro-6-quinolinecarboxylic acid; 3-Fluoroquinoline-6-carboxylate; 1824275-93-5; 3-Fluoro-6-carboxyquinoline; 6-Carboxy-3-fluoroquinoline; 3-Fluoro-6-quinoline carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoroquinoline-6-Carboxylic Acid is manufactured and tested under strict quality management protocols. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development applications. A detailed Certificate of Analysis (COA) including purity by HPLC, identity confirmation (IR, NMR), and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.