Description

2-Fluoro-4-Bromo-6-Chlorobenzyl Bromide is a high-value, multi-halogenated benzyl bromide derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an essential reagent for introducing a reactive benzyl moiety with orthogonal halogen handles for further functionalization. This compound is primarily sought after by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the fluorine and halogen atoms for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in cross-coupling catalysis and organometallic chemistry.
• Material Science Research: Building block for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up campaigns.
• Academic & Industrial R&D: Utilized in research laboratories for methodological development and exploring new chemical spaces in medicinal chemistry.

Basic Information

Product Name	2-Fluoro-4-Bromo-6-Chlorobenzyl Bromide
CAS No.	1823959-60-9
Molecular Formula	C7H4Br2ClF
Molecular Weight	306.37 g/mol
Synonyms	1-(Bromomethyl)-2-fluoro-4-bromo-6-chlorobenzene; (4-Bromo-2-chloro-6-fluorophenyl)methyl Bromide; 2-Fluoro-4,6-dibromochlorotoluene (brominated derivative); α-Bromo-2-fluoro-4-bromo-6-chlorotoluene; Benzene, 1-(bromomethyl)-2-fluoro-4-bromo-6-chloro-; 4-Bromo-2-chloro-6-fluorobenzyl Bromide
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4-Bromo-6-Chlorobenzyl Bromide is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC/GC and NMR is supplied with each shipment. Our quality commitment ensures batch-to-batch consistency and reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.