Description

2-(Trifluoromethyl)Isonicotinamide is a high-purity fluorinated pyridine derivative, a key building block in advanced organic synthesis. Its value lies in the unique reactivity imparted by the trifluoromethyl group, which is critical for modulating the physicochemical properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial synthon for the research and development of new drug candidates, especially in kinase inhibitor and antiviral programs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, where the CF3 group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers in the development of specialty polymers and advanced materials.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and probes for studying biological mechanisms and target engagement.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring the introduction of a trifluoromethyl-substituted pyridine moiety.

Basic Information

Product Name	2-(Trifluoromethyl)Isonicotinamide
CAS No.	1823892-98-3
Molecular Formula	C7H5F3N2O
Molecular Weight	190.12 g/mol
Synonyms	2-(Trifluoromethyl)pyridine-4-carboxamide; 4-Pyridinecarboxamide, 2-(trifluoromethyl)-; Isonicotinamide, 2-(trifluoromethyl)-; 2-Trifluoromethylisonicotinamide; 2-Carbamoyl-4-(trifluoromethyl)pyridine; 4-Carbamoyl-2-(trifluoromethyl)pyridine; 2-(Trifluoromethyl)isonicotinic acid amide
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethyl)Isonicotinamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment is to supply material that meets the exacting standards required for research and cGMP-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.