Description

1-Bromo-2-Chloro-4-Fluoro-5-Methoxy-Benzene is a high-purity, multi-substituted benzene derivative designed for advanced chemical synthesis. This compound serves as a critical building block in the development of complex molecules, offering precise halogen and methoxy functionalization for regioselective coupling and substitution reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for their R&D and production processes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing halogenated aromatic systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where the specific halogen pattern is crucial for bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of advanced polymers and liquid crystals.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to construct complex molecular architectures.
• Chemical Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	1-Bromo-2-Chloro-4-Fluoro-5-Methoxy-Benzene
CAS No.	1823372-35-5
Molecular Formula	C7H5BrClFO
Molecular Weight	239.47 g/mol
Synonyms	2-Bromo-1-Chloro-4-Fluoro-5-Methoxybenzene; 5-Bromo-4-Chloro-2-Fluoroanisole; Benzene, 1-bromo-2-chloro-4-fluoro-5-methoxy-; 4-Fluoro-5-methoxy-2-bromo-1-chlorobenzene; 1-Chloro-2-bromo-4-fluoro-5-methoxybenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Chloro-4-Fluoro-5-Methoxy-Benzene is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.