Description

Gsk-Lsd1 Dihydrochloride is a potent and selective lysine-specific demethylase 1 (LSD1) inhibitor, supplied as a high-purity dihydrochloride salt. This compound is a critical research tool for investigating epigenetic regulation, cellular differentiation, and gene expression pathways. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on oncology, neurology, and metabolic disease research.

Application

• Biochemical Research: Used as a reference standard and active agent in enzymatic assays to study LSD1/KDM1A inhibition and its role in histone modification.
• Pharmaceutical Development: Serves as a key intermediate or pharmacologically active compound in the discovery and preclinical development of novel epigenetic therapies.
• Cell Biology Studies: Applied in vitro to investigate the effects of LSD1 inhibition on cell proliferation, differentiation, and stem cell pluripotency.
• Oncology Research: Explored for its potential to modulate gene expression in various cancer cell lines, aiding in target validation and mechanism-of-action studies.
• Neuroscience Research: Utilized in models to understand the epigenetic underpinnings of neurological disorders and potential therapeutic interventions.

Basic Information

Product Name	Gsk-Lsd1 Dihydrochloride
CAS No.	1821798-25-7
Molecular Formula	C23H27Cl2N5O3
Molecular Weight	492.40 g/mol
Synonyms	GSK-LSD1 dihydrochloride; GSK2879552 dihydrochloride; (1R,3S)-3-[2-(3-Fluorophenyl)ethyl]-5-[[(trans)-4-(2-methoxyethylamino)cyclohexyl]amino]methyl]-1-methyl-1,3-dihydro-2H-indol-2-one dihydrochloride; LSD1 Inhibitor GSK2879552 diHCl; GSK' LSD1 inhibitor; KDM1A Inhibitor GSK2879552
EINECS	Contact for details

Quality Control

Our Gsk-Lsd1 Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided to ensure traceability and compliance with research-grade material standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to warm to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.