Description

Hdac6-In-1 CAS NO 1815580-06-3 is a potent and selective small molecule inhibitor targeting histone deacetylase 6 (HDAC6). This compound is a critical research tool for investigating the role of HDAC6 in cellular processes, offering high selectivity to minimize off-target effects. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on oncology, neurodegenerative diseases, and immunology research.

Application

• Biochemical Research: Used as a selective probe to study HDAC6 enzyme kinetics, substrate specificity, and inhibition mechanisms in vitro.
• Cell-Based Assays: Employed to investigate the biological consequences of HDAC6 inhibition on cell proliferation, apoptosis, and protein acetylation levels.
• Drug Discovery & Development: Serves as a lead compound or reference standard in the development of novel HDAC6-targeted therapeutics for cancer and other diseases.
• Neuroscience Research: Applied in models to study the role of HDAC6 in tauopathy, axonal transport, and neurodegenerative conditions like Alzheimer's disease.
• Immunology Studies: Used to explore the modulation of immune cell function and cytokine production through HDAC6 inhibition.
• Target Validation: A key tool for validating HDAC6 as a therapeutic target in various preclinical disease models.

Basic Information

Item	Details
Product Name	Hdac6-In-1
CAS No.	1815580-06-3
Molecular Formula	C₂₀H₂₀N₄O₃
Molecular Weight	364.40 g/mol
Synonyms	HDAC6-IN-1; (E)-N-Hydroxy-4-((2-(2-methyl-1H-indol-3-yl)ethyl)amino)benzamide; HDAC6 Inhibitor; Histone Deacetylase 6 Inhibitor; 1815580-06-3; (E)-4-[[2-(2-Methyl-1H-indol-3-yl)ethyl]amino]-N-oxidobenzamide; HDAC6 Selective Inhibitor
EINECS	Contact for details

Quality Control

Our Hdac6-In-1 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity confirmation, NMR and MS for structural identity, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. The product is light-sensitive (store away from light). Allow the vial to warm to room temperature in a desiccator before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular ion [M+H]+
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.