Description

(2-Ethoxy-5-Fluoropyridin-4-Yl)Methanol is a high-value fluorinated pyridine derivative, serving as a critical building block in modern synthetic chemistry. Its unique structure, featuring both a fluorinated aromatic ring and a hydroxymethyl group, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its modifiable hydroxymethyl group.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	(2-Ethoxy-5-Fluoropyridin-4-Yl)Methanol
CAS No.	1809158-12-0
Molecular Formula	C8H10FNO2
Molecular Weight	171.17 g/mol
Synonyms	4-(Hydroxymethyl)-2-ethoxy-5-fluoropyridine; 5-Fluoro-2-ethoxy-4-pyridinemethanol; 2-Ethoxy-5-fluoro-4-pyridinemethanol; (2-Ethoxy-5-fluoro-4-pyridinyl)methanol; 5-Fluoro-2-ethoxypyridine-4-methanol; 4-Pyridinemethanol, 2-ethoxy-5-fluoro-; 1809158-12-0; (2-Ethoxy-5-fluoropyridin-4-yl)methanol
EINECS	Contact for details

Quality Control

Our (2-Ethoxy-5-Fluoropyridin-4-Yl)Methanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the stringent requirements of advanced R&D and scale-up processes. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.