Description

1-(3-Bromo-6-Fluoropyridin-2-Yl)Ethanone is a high-purity fluorinated pyridine derivative, a crucial building block in advanced organic synthesis. Its value lies in its unique halogenated structure, which enables precise molecular modifications essential for developing novel active compounds. This intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug research.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging the fluorine and bromine substituents for enhanced bioactivity.
• Material Science Research: Used in the synthesis of functionalized ligands and organic electronic materials due to its electron-withdrawing properties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions, facilitating the construction of complex biaryl systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring high-fidelity halogenated intermediates.

Basic Information

Product Name	1-(3-Bromo-6-Fluoropyridin-2-Yl)Ethanone
CAS No.	1807542-88-6
Molecular Formula	C7H5BrFNO
Molecular Weight	218.03 g/mol
Synonyms	2-Acetyl-3-bromo-6-fluoropyridine; 3-Bromo-6-fluoro-2-acetylpyridine; 1-(3-Bromo-6-fluoro-2-pyridinyl)ethanone; Ethanone, 1-(3-bromo-6-fluoro-2-pyridinyl)-; 1807542-88-6; 3-Bromo-6-fluoro-2-pyridyl methyl ketone
EINECS	Contact for details

Quality Control

Our production of 1-(3-Bromo-6-Fluoropyridin-2-Yl)Ethanone adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.