Description

5-Fluoro-6-(Trifluoromethyl)Nicotinonitrile 95+% is a high-purity, multi-fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique trifluoromethyl and cyano substituents on the pyridine core make it a valuable scaffold for introducing specific physicochemical properties into target molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity, metabolic stability, and lipophilicity.
• Material Science: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and electronic materials requiring specific dielectric properties.
• Chemical Biology Probe: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and as a fragment in fragment-based drug discovery (FBDD) due to its distinct three-dimensional shape and polarity.
• Fluorinated Building Block: Provides a versatile handle for further functionalization via the reactive cyano group, enabling the construction of complex heterocyclic systems like pyrimidines, triazoles, and amides.

Basic Information

Product Name	5-Fluoro-6-(Trifluoromethyl)Nicotinonitrile 95+%
CAS No.	1807303-10-1
Molecular Formula	C7H2F4N2
Molecular Weight	190.10 g/mol
Synonyms	5-Fluoro-6-(trifluoromethyl)pyridine-3-carbonitrile; 3-Cyano-5-fluoro-6-(trifluoromethyl)pyridine; 5-Fluoro-6-trifluoromethylnicotinonitrile; 5-Fluoro-6-(trifluoromethyl)-3-pyridinecarbonitrile; 1807303-10-1; 5-Fluoro-6-(trifluoromethyl)-3-cyanopyridine; Nicotinonitrile, 5-fluoro-6-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 5-Fluoro-6-(Trifluoromethyl)Nicotinonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the specified 95+% purity grade. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.