Description

1-Bromo-2,6-Difluoro-3-(Difluoromethoxy)Benzene is a high-purity, multi-functional fluorinated aromatic building block essential for advanced organic synthesis. Its unique structure, featuring bromine and fluorine substituents, makes it a critical intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where the difluoromethoxy group can enhance metabolic stability and bioavailability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated aromatic cores for advanced electronic materials used in displays and organic light-emitting diodes.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to construct complex biaryl systems.
• Fluorine Chemistry Research: An important reagent for studying structure-activity relationships (SAR) and the effects of fluorine substitution in medicinal and material chemistry.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals, dyes, and functional polymers requiring specific halogenated motifs.

Basic Information

Product Name	1-Bromo-2,6-Difluoro-3-(Difluoromethoxy)Benzene
CAS No.	1807172-54-8
Molecular Formula	C7H3BrF4O
Molecular Weight	274.99 g/mol
Synonyms	3-Bromo-2,6-difluoro-1-(difluoromethoxy)benzene; 2,6-Difluoro-3-(difluoromethoxy)bromobenzene; 1-Bromo-2,6-difluoro-3-(difluoromethoxy)benzene; Benzene, 1-bromo-2,6-difluoro-3-(difluoromethoxy)-; 3-(Difluoromethoxy)-2,6-difluorobromobenzene; CAS 1807172-54-8
EINECS	Contact for details

Quality Control

Every batch of 1-Bromo-2,6-Difluoro-3-(Difluoromethoxy)Benzene is manufactured and tested under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.