Description

(4-Chloro-5-Fluoropyridin-3-Yl)Methanol is a high-value fluorinated pyridine derivative, serving as a critical building block in modern synthetic chemistry. Its molecular structure, featuring both chloro and fluoro substituents on the pyridine ring, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients. Its reliable quality and consistent supply are paramount for accelerating drug discovery and crop protection product development pipelines.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers used in creating specialty polymers and advanced materials.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	(4-Chloro-5-Fluoropyridin-3-Yl)Methanol
CAS No.	1807166-44-4
Molecular Formula	C6H5ClFNO
Molecular Weight	161.56 g/mol
Synonyms	3-(Hydroxymethyl)-4-chloro-5-fluoropyridine; 4-Chloro-5-fluoro-3-pyridinemethanol; (4-Chloro-5-fluoro-3-pyridinyl)methanol; 5-Fluoro-4-chloropyridin-3-ylmethanol; 4-Chloro-5-fluoro-3-(hydroxymethyl)pyridine; 3-Pyridinemethanol, 4-chloro-5-fluoro-; 1807166-44-4
EINECS	Contact for details

Quality Control

Every batch of (4-Chloro-5-Fluoropyridin-3-Yl)Methanol is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting industry standards and customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.