Description

2-Fluoro-3-Iodo-4-Pyridinamine is a high-value, multi-functional halogenated pyridine derivative, distinguished by its unique substitution pattern. This compound serves as a critical pharmaceutical intermediate and versatile building block in advanced organic synthesis, enabling the development of novel active compounds. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for creating targeted molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, antiviral agents, and other small-molecule drug candidates.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and pesticides with specific modes of action.
• Ligand Synthesis: Serves as a building block for creating complex ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design of molecular probes for studying biological pathways and protein interactions.
• Organic Electronics: A potential component in the synthesis of advanced materials for electronic applications.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).

Basic Information

Product Name	2-Fluoro-3-Iodo-4-Pyridinamine
CAS No.	1807159-94-9
Molecular Formula	C5H4FIN2
Molecular Weight	237.99 g/mol
Synonyms	4-Amino-2-fluoro-3-iodopyridine; 3-Iodo-2-fluoropyridin-4-amine; 2-Fluoro-3-iodopyridin-4-amine; 4-Pyridinamine, 2-fluoro-3-iodo-; 2-Fluoro-3-iodo-4-aminopyridine; 2-F-3-I-4-AP; 1807159-94-9
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Iodo-4-Pyridinamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.