Description

2-Bromo-3,5-Difluorotoluene is a halogenated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and functionalized ligands for catalysis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those containing difluoromethyl and aryl bromide motifs for cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of new herbicides and pesticides, leveraging its halogen and fluorine substituents for bioactivity.
• Material Science: Serves as a building block for organic electronic materials, including ligands for OLEDs and liquid crystals, due to its stable aromatic core and halogen functionality.
• Chemical Research: Employed in academic and industrial laboratories for method development in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Fluorine Chemistry: A valuable substrate for further functionalization, exploring the unique properties imparted by the fluorine atoms.

Basic Information

Product Name	2-Bromo-3,5-Difluorotoluene
CAS No.	1807135-08-5
Molecular Formula	C7H5BrF2
Molecular Weight	207.02 g/mol
Synonyms	1-Bromo-2,4-difluoro-5-methylbenzene; 2,4-Difluoro-5-methylbromobenzene; 3,5-Difluoro-2-bromotoluene; Toluene, 2-bromo-3,5-difluoro-; 5-Methyl-2,4-difluorobromobenzene; 2-Bromo-3,5-difluoro-1-methylbenzene; α,α,α-Trifluoro-2-bromo-5-fluorotoluene (isomer specific); Benzene, 1-bromo-2,4-difluoro-5-methyl-
EINECS	Contact for details

Quality Control

Our 2-Bromo-3,5-Difluorotoluene is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids, organic solvents, fluorides, and strong alkalis. The container should be kept tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.