Description

4-Bromo-2-Fluoro-5-Iodo-Pyridine is a high-value, multi-halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an indispensable intermediate for constructing complex molecules, particularly in pharmaceutical and agrochemical research. This compound is primarily sought by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Building block for developing new generation herbicides, fungicides, and insecticides with enhanced activity.
• Material Science: Used in the creation of organic electronic materials, liquid crystals, and ligands for catalytic systems.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi cross-coupling reactions due to the presence of bromine and iodine substituents.
• Functional Group Transformation: Serves as a versatile starting material for selective functionalization via halogen-metal exchange or nucleophilic aromatic substitution.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags for imaging and diagnostic applications.

Basic Information

Product Name	4-Bromo-2-Fluoro-5-Iodo-Pyridine
CAS No.	1807119-09-0
Molecular Formula	C5H2BrFIN
Molecular Weight	301.88 g/mol
Synonyms	5-Iodo-4-bromo-2-fluoropyridine; 2-Fluoro-4-bromo-5-iodopyridine; 4-Bromo-2-fluoro-5-iodopyridine; Pyridine, 4-bromo-2-fluoro-5-iodo-; 1807119-09-0; 4-Br-2-F-5-I-Pyridine
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluoro-5-Iodo-Pyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality system supports compliance with relevant guidelines for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.