Description

2,5-Dibromo-3-Fluorobenzodifluoride is a high-value, multi-halogenated aromatic building block of significant interest in advanced organic synthesis. Its precise molecular architecture, featuring bromine and fluorine substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing halogenated aromatic motifs that can influence bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the dibromo-fluorobenzodifluoride scaffold contributes to pesticidal activity and environmental persistence profiles.
• Liquid Crystal & OLED Materials: Acts as a building block for fluorine-containing organic electronic materials, enabling the fine-tuning of dielectric constants, refractive indices, and charge transport properties in displays and lighting.
• Polymer & Resin Modifier: Incorporated into specialty polymers to enhance flame retardancy, chemical resistance, and thermal stability through halogenated aromatic units.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi), allowing for the sequential functionalization of the aromatic ring.
• Fluorinated Surfactant & Lubricant Research: Provides a fluorinated aromatic core for developing novel surfactants and high-performance lubricants with low surface energy.

Basic Information

Product Name	2,5-Dibromo-3-Fluorobenzodifluoride
CAS No.	1807056-00-3
Molecular Formula	C7H2Br2F3
Molecular Weight	309.90 g/mol
Synonyms	1,2-Dibromo-4-fluoro-5-(trifluoromethyl)benzene; 3-Fluoro-2,5-dibromobenzotrifluoride; 2,5-Dibromo-α,α,α-trifluoro-m-fluorotoluene; Benzene, 1,2-dibromo-4-fluoro-5-(trifluoromethyl)-; 2,5-Dibromo-3-fluorobenzotrifluoride
EINECS	Contact for details

Quality Control

Our 2,5-Dibromo-3-Fluorobenzodifluoride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity chemical intermediates for research and scale-up.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reactive metals. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.