Description

6-Bromo-4-(Trifluoromethyl)Nicotinonitrile is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. Its core value lies in the strategic combination of a bromo substituent and a trifluoromethyl group on a nicotinonitrile scaffold, offering versatile reactivity for molecular diversification. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it serves as a critical intermediate in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Material Science: Serves as a building block for advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Synthesis: The bromine atom facilitates further functionalization via cross-coupling reactions (e.g., Suzuki, Negishi), while the nitrile group can be transformed into various other functionalities.
• Ligand & Catalyst Development: Employed in the design of novel ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	6-Bromo-4-(Trifluoromethyl)Nicotinonitrile
CAS No.	1807025-03-1
Molecular Formula	C7H2BrF3N2
Molecular Weight	250.99 g/mol
Synonyms	6-Bromo-4-(trifluoromethyl)pyridine-3-carbonitrile; 3-Cyano-6-bromo-4-(trifluoromethyl)pyridine; 6-Bromo-4-trifluoromethylnicotinonitrile; 6-Bromo-4-trifluoromethyl-3-pyridinecarbonitrile; 6-Bromo-4-(trifluoromethyl)-3-pyridinecarbonitrile; 6-Bromo-4-(trifluoromethyl)-3-cyanopyridine; 6-Bromo-4-(trifluoromethyl)nicotinonitrile; 1807025-03-1
EINECS	Contact for details

Quality Control

Our 6-Bromo-4-(Trifluoromethyl)Nicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.