Description

5-Bromo-2-Chloro-3-Fluorotoluene is a high-purity halogenated toluene derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in providing a versatile, multi-functional aromatic scaffold for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research chemists and process development teams in fine chemical, pharmaceutical, and material science industries seeking to introduce specific halogen substitutions for downstream functionalization.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules requiring specific halogen patterns for bioactivity or as a handle for further coupling reactions.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the bromo and chloro groups are pivotal for efficacy.
• Material Science Precursor: Serves as a monomer or precursor for the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination, leveraging the reactive bromo substituent.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and constructing complex heterocyclic compounds.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized halogenated dyes and pigments.

Basic Information

Product Name	5-Bromo-2-Chloro-3-Fluorotoluene
CAS No.	1806971-86-7
Molecular Formula	C7H5BrClF
Molecular Weight	223.47 g/mol
Synonyms	1-Bromo-4-chloro-5-fluoro-2-methylbenzene; 2-Chloro-5-bromo-3-fluorotoluene; 3-Fluoro-2-chloro-5-bromotoluene; Toluene, 5-bromo-2-chloro-3-fluoro-; 2-Methyl-1-bromo-4-chloro-5-fluorobenzene; 5-Bromo-2-chloro-3-fluoro-1-methylbenzene
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2-Chloro-3-Fluorotoluene is manufactured and tested under a strict quality management system. We guarantee high chemical purity and consistency, supported by comprehensive analytical documentation. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to ensure it meets your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.