Description

5-Bromo-6-Fluoropicolinonitrile is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique halogenated pyridine structure, which provides versatile reactivity for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for use as a key intermediate in the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Serves as a versatile scaffold for developing new herbicides, fungicides, and insecticides, leveraging the bioactivity of halogenated pyridine derivatives.
• Material Science: Used in the research and development of advanced organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Chemical Biology Probe Synthesis: Employed to create labeled compounds and molecular probes for studying biological pathways and enzyme functions.
• Cross-Coupling Reactions: Acts as a valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex substituents.

Basic Information

Product Name	5-Bromo-6-Fluoropicolinonitrile
CAS No.	1806849-64-8
Molecular Formula	C6H2BrFN2
Molecular Weight	200.99 g/mol
Synonyms	5-Bromo-6-fluoropyridine-2-carbonitrile; 2-Cyano-5-bromo-6-fluoropyridine; 6-Fluoro-5-bromopicolinonitrile; 5-Bromo-6-fluoro-2-pyridinecarbonitrile; 5-Bromo-6-fluoropyridine-2-carbonitrile; 1806849-64-8
EINECS	Contact for details

Quality Control

Our 5-Bromo-6-Fluoropicolinonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.