Description

Methyl 4-Amino-6-Fluoronicotinate is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which incorporates both amino and fluorine substituents on the nicotinate core, enabling precise modifications in complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine-tuning the properties of target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes and material science.
• Fluorinated Building Block: Employed in medicinal chemistry for the strategic introduction of fluorine to improve metabolic stability and membrane permeability of lead compounds.
• Chemical Research: Utilized in academic and industrial R&D for exploring new reactions and synthesizing complex heterocyclic systems.
• Fine Chemical Production: Acts as a starting material for the manufacture of other high-value, specialty fluorinated chemicals.

Basic Information

Product Name	Methyl 4-Amino-6-Fluoronicotinate
CAS No.	1806662-80-5
Molecular Formula	C7H7FN2O2
Molecular Weight	170.14 g/mol
Synonyms	Methyl 4-Amino-6-Fluoropyridine-3-carboxylate; 6-Fluoro-4-aminonicotinic Acid Methyl Ester; 4-Amino-6-fluoro-3-pyridinecarboxylic Acid Methyl Ester; 3-Pyridinecarboxylic acid, 4-amino-6-fluoro-, methyl ester; Methyl 4-Amino-6-Fluoronicotinate; 1806662-80-5
EINECS	Contact for details

Quality Control

Our Methyl 4-Amino-6-Fluoronicotinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.