Description

Methyl 4,6-Difluoropyridine-3-Carboxylate CAS NO 1806389-22-9 is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique difluoropyridine scaffold, which is essential for modulating the physicochemical and metabolic properties of target molecules. This intermediate is primarily needed by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, including kinase inhibitors and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides with enhanced efficacy and environmental profiles.
• Material Science Precursor: Employed in the development of specialty chemicals, ligands for catalysis, and advanced functional materials.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies.

Basic Information

Product Name	Methyl 4,6-Difluoropyridine-3-Carboxylate
CAS No.	1806389-22-9
Molecular Formula	C7H5F2NO2
Molecular Weight	173.12 g/mol
Synonyms	3-Pyridinecarboxylic acid, 4,6-difluoro-, methyl ester; Methyl 4,6-difluoronicotinate; 4,6-Difluoropyridine-3-carboxylic acid methyl ester; Methyl 4,6-difluoropyridine-3-carboxylate; 4,6-Difluoro-3-pyridinecarboxylic acid methyl ester; Methyl 4,6-difluoro-3-pyridinecarboxylate; 1806389-22-9
EINECS	Contact for details

Quality Control

Our Methyl 4,6-Difluoropyridine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.