Description

Ethyl 3-Fluoro-6-(trifluoromethyl)pyridine-2-carboxylate is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and a trifluoromethyl group, is engineered to impart enhanced metabolic stability, lipophilicity, and bioavailability to target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with improved performance profiles.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and antiviral research.
• Agrochemical Synthesis: Used in the creation of next-generation herbicides, insecticides, and fungicides that require fluorinated motifs for efficacy and environmental persistence.
• Material Science Research: Serves as a precursor for specialty chemicals, liquid crystals, and advanced polymers where fluorine substitution modifies electronic and surface properties.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and tags for imaging and diagnostic applications due to the distinct properties of fluorine.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up services for clients in fine chemical production.

Basic Information

Product Name	Ethyl 3-Fluoro-6-(Trifluoromethyl)Pyridine-2-Carboxylate
CAS No.	1806386-01-5
Molecular Formula	C9H7F4NO2
Molecular Weight	237.15 g/mol
Synonyms	Ethyl 3-fluoro-6-(trifluoromethyl)picolinate; 2-Pyridinecarboxylic acid, 3-fluoro-6-(trifluoromethyl)-, ethyl ester; 3-Fluoro-6-(trifluoromethyl)picolinic acid ethyl ester; Ethyl 3-fluoro-6-(trifluoromethyl)-2-pyridinecarboxylate; 1806386-01-5; Ethyl 3-fluoro-6-trifluoromethylpicolinate
EINECS	Contact for details

Quality Control

Our Ethyl 3-Fluoro-6-(Trifluoromethyl)Pyridine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for GLP and cGMP development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.