Description

3,5-Dibromo-2-Fluorobenzotrifluoride is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogenated trifluoromethylbenzene structure enables precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorine and bromine substituents for tuning bioactivity and material properties.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine and bromine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated compounds used in electronic displays and organic light-emitting diodes (OLEDs) due to its influence on electronic properties.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart flame retardancy, chemical resistance, and altered refractive indices.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions, enabling the construction of complex biaryl systems.
• Chemical Research & Development: A valuable reagent for academic and industrial research exploring new fluorination methodologies and heterocyclic chemistry.

Basic Information

Product Name	3,5-Dibromo-2-Fluorobenzotrifluoride
CAS No.	1806353-73-0
Molecular Formula	C7H2Br2F4
Molecular Weight	345.90 g/mol
Synonyms	2-Fluoro-3,5-dibromobenzotrifluoride; 1,3-Dibromo-2-fluoro-5-(trifluoromethyl)benzene; 3,5-Dibromo-2-fluoro-α,α,α-trifluorotoluene; 2-Fluoro-α,α,α-trifluoro-3,5-dibromotoluene; Benzene, 1,3-dibromo-2-fluoro-5-(trifluoromethyl)-; 3,5-Dibromo-2-fluorobenzylidene trifluoride
EINECS	Contact for details

Quality Control

Our 3,5-Dibromo-2-Fluorobenzotrifluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP standards where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to prevent moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.