Description

3,5-Difluoro-4-Nitrobenzaldehyde is a high-purity fluorinated aromatic aldehyde building block, distinguished by its strategically positioned nitro and aldehyde functional groups. This compound is critical for advanced organic synthesis, enabling the precise construction of complex molecules with tailored electronic and steric properties. It is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a difluorinated aromatic core for metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, where the nitro and aldehyde groups serve as handles for further functionalization.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Functional Material Precursor: Employed in the research and production of advanced polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing substituents.
• Chemical Biology Probes: Utilized in the design and synthesis of fluorescent tags, molecular probes, and other tools for biochemical research.
• Custom Synthesis and R&D: A versatile building block for contract research organizations (CROs) and academic laboratories exploring novel chemical space and reaction methodologies.

Basic Information

Product Name	3,5-Difluoro-4-Nitrobenzaldehyde
CAS No.	1806335-15-8
Molecular Formula	C7H3F2NO3
Molecular Weight	187.10 g/mol
Synonyms	4-Nitro-3,5-difluorobenzaldehyde; 3,5-Difluoro-4-nitrobenzaldehyde; Benzaldehyde, 3,5-difluoro-4-nitro-; 3,5-Difluoro-4-nitro-benzaldehyde; 1806335-15-8
EINECS	Contact for details

Quality Control

Every batch of 3,5-Difluoro-4-Nitrobenzaldehyde is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) specifying identity, purity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Yellow to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.