Description

2,4-Difluoro-5-Hydroxybenzaldehyde is a high-value fluorinated aromatic aldehyde building block. This compound is essential for the synthesis of complex molecules, where its unique substitution pattern enables precise structural modifications. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated cores in electronic display materials and organic light-emitting diodes (OLEDs), improving charge transport and emission efficiency.
• Advanced Polymer Chemistry: Employed as a monomer or cross-linking agent to introduce fluorine and aldehyde functionality into specialty polymers, enhancing thermal and chemical resistance.
• Chemical Research & Development: A versatile building block in medicinal chemistry and material science for structure-activity relationship (SAR) studies and library synthesis.
• Fluorescent Probe & Dye Synthesis: Used to create fluorophores and molecular probes for bio-imaging and diagnostic applications due to its derivatizable aldehyde group.

Basic Information

Product Name	2,4-Difluoro-5-Hydroxybenzaldehyde
CAS No.	1806330-57-3
Molecular Formula	C7H4F2O2
Molecular Weight	158.10 g/mol
Synonyms	5-Hydroxy-2,4-difluorobenzaldehyde; 2,4-Difluoro-5-hydroxybenzaldehyde; 2,4-Difluoro-5-hydroxybenzenecarboxaldehyde; 5-Hydroxy-2,4-difluorobenzenecarbaldehyde; Benzaldehyde, 2,4-difluoro-5-hydroxy-; 1806330-57-3
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-5-Hydroxybenzaldehyde is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and hygroscopic (moisture-sensitive). Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.