Description

2-Fluoro-1-Iodo-3,4-Dimethyl-Benzene is a high-purity, halogenated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile intermediate, enabling the precise introduction of fluorine and iodine substituents into complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, where the fluorine atom can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for creating advanced organic electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira, Negishi) due to the reactive iodine moiety, facilitating carbon-carbon bond formation.
• Fluorine Chemistry Research: A valuable reagent in academic and industrial laboratories focused on exploring new methodologies in organofluorine chemistry.
• Ligand & Catalyst Development: Employed in the synthesis of specialized ligands and organocatalysts for asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	2-Fluoro-1-Iodo-3,4-Dimethyl-Benzene
CAS No.	1806323-40-9
Molecular Formula	C8H8FI
Molecular Weight	250.05 g/mol
Synonyms	1-Fluoro-2-iodo-4,5-dimethylbenzene; 3,4-Dimethyl-2-fluoroiodobenzene; 2-Fluoro-3,4-dimethyl-1-iodobenzene; 2-Fluoro-1-iodo-3,4-dimethylbenzene; 1-Iodo-2-fluoro-3,4-dimethylbenzene; 4,5-Dimethyl-2-fluoro-1-iodobenzene; Benzene, 2-fluoro-1-iodo-3,4-dimethyl-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are available upon request. We adhere to strict quality management protocols to support your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.