Description

2-Fluoro-4-Bromo-6-Chlorotoluene is a high-purity halogenated toluene derivative, a crucial building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which provides multiple reactive sites for constructing complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, where the fluorine and halogen atoms enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic aromatic substitution to create complex, multi-substituted aromatic systems for discovery chemistry.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing specialized halogenated dyes and pigments with unique color fastness and spectral properties.

Basic Information

Product Name	2-Fluoro-4-Bromo-6-Chlorotoluene
CAS No.	1806058-46-7
Molecular Formula	C7H5BrClF
Molecular Weight	223.47 g/mol
Synonyms	1-Bromo-3-chloro-5-fluoro-2-methylbenzene; 2-Methyl-1-bromo-3-chloro-5-fluorobenzene; Toluene, 2-fluoro-4-bromo-6-chloro-; 4-Bromo-2-chloro-6-fluorotoluene; 2-Chloro-6-fluoro-4-bromotoluene; 6-Chloro-2-fluoro-4-bromotoluene
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4-Bromo-6-Chlorotoluene is manufactured and tested under a strict quality management system. We guarantee high chemical purity and consistency, supported by comprehensive analytical documentation. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles via HPLC, GC, and NMR is provided with each shipment to ensure it meets your precise research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.