Description

Jak3-In-1 CAS NO 1805787-93-2 is a potent and selective small molecule inhibitor targeting the Janus kinase 3 (JAK3) signaling pathway. This compound is of significant value for research and development in immunology and oncology, offering a critical tool for modulating cytokine-mediated responses. It is primarily needed by pharmaceutical researchers, biotechnology companies, and academic institutions engaged in the discovery of novel therapeutics for autoimmune diseases, inflammatory conditions, and certain cancers.

Application

• Biomedical Research: A key reagent for studying JAK-STAT signaling pathways, cellular proliferation, and immune cell function in vitro.
• Drug Discovery & Development: Serves as a reference standard and a lead compound in high-throughput screening and preclinical studies for JAK3-targeted therapies.
• Immunology Studies: Used to investigate the role of JAK3 in T-cell and B-cell activation, differentiation, and related autoimmune disorders.
• Oncology Research: Applied in research exploring JAK3 inhibition as a potential therapeutic strategy for hematological malignancies and solid tumors.
• Biochemical Assay Development: Employed as a critical component in developing and validating enzymatic assays to screen for new JAK3 inhibitors.

Basic Information

Product Name	Jak3-In-1
CAS No.	1805787-93-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	JAK3-IN-1; Jak3 Inhibitor-1; 1805787-93-2; Janus Kinase 3 Inhibitor-1; JAK3i-1; (S)-N-(4-(1-Acetylpiperidin-4-yl)phenyl)-1H-pyrrolo[2,3-b]pyridine-5-carboxamide; (S)-1-(4-(1-Acetylpiperidin-4-yl)phenyl)-1H-pyrrolo[2,3-b]pyridine-5-carboxamide
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research chemicals. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and stability. Certificates of Analysis (COA) detailing specific lot results are available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥95%
Water Content	≤1.0%
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.