Description

6-Fluoro-3-Methoxypyridin-2-Amine is a high-purity, multi-functional pyridine derivative building block essential for modern organic synthesis. This compound matters for its role as a key intermediate in the development of advanced pharmaceuticals and agrochemicals, where its unique fluorine and methoxy substitution pattern enables precise molecular design. It is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging its fluorine atom for enhanced bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the creation of organic electronic materials, such as charge-transport layers or light-emitting components, due to its electron-donating amine and methoxy groups.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and fluorescent tags for biological imaging and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific fluorinated pyridine motifs.

Basic Information

Product Name	6-Fluoro-3-Methoxypyridin-2-Amine
CAS No.	1805602-80-5
Molecular Formula	C6H7FN2O
Molecular Weight	142.13 g/mol
Synonyms	2-Amino-6-fluoro-3-methoxypyridine; 3-Methoxy-6-fluoropyridin-2-amine; 6-Fluoro-3-methoxy-2-pyridinamine; 2-Pyridinamine, 6-fluoro-3-methoxy-; 6-Fluoro-3-methoxypyridin-2-ylamine; 6-Fluoro-3-methoxy-2-aminopyridine; 2-Amino-6-fluoro-3-methoxypyridine
EINECS	Contact for details

Quality Control

Our 6-Fluoro-3-Methoxypyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in cGMP and ISO 9001 environments for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.