Description

5-Bromo-4-Fluoropyridin-2(1H)-One is a high-value, halogenated pyridinone derivative serving as a critical building block in modern synthetic chemistry. This compound is essential for the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals, where its unique substitution pattern enables precise molecular modifications. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex heterocyclic scaffolds in drug discovery, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a precursor for functionalized ligands and organic electronic materials due to its electron-withdrawing bromo and fluoro substituents.
• Chemical Biology Probes: Employed in the synthesis of tagged molecules and probes for studying biological pathways and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	5-Bromo-4-Fluoropyridin-2(1H)-One
CAS No.	1805590-93-5
Molecular Formula	C5H3BrFNO
Molecular Weight	191.99 g/mol
Synonyms	5-Bromo-4-fluoro-1,2-dihydropyridin-2-one; 5-Bromo-4-fluoro-2-hydroxypyridine; 5-Bromo-4-fluoro-2-pyridone; 2(1H)-Pyridinone, 5-bromo-4-fluoro-; 5-Bromo-4-fluoro-1H-pyridin-2-one; 4-Fluoro-5-bromopyridin-2(1H)-one
EINECS	Contact for details

Quality Control

Our production of 5-Bromo-4-Fluoropyridin-2(1H)-One adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. All materials are characterized by modern analytical techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.