Description

1,3-Bis(Trifluoromethyl)-2,4-Dibromobenzene is a highly functionalized aromatic building block, specifically engineered for advanced synthesis. Its unique structure, featuring both bromine and trifluoromethyl groups, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated aromatic cores to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a sophisticated backbone for creating specialized ligands in transition metal catalysis and organocatalysis.
• Functional Material Precursor: Employed in the research and production of advanced materials, such as liquid crystals, organic semiconductors, and polymers with specific optical or electronic properties.
• Cross-Coupling Reactions: The bromine substituents make it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Stille) to form complex biaryl structures.
• Fluorine Chemistry Research: An essential compound for academic and industrial research focused on introducing and studying the effects of fluorine atoms in organic molecules.

Basic Information

Product Name	1,3-Bis(Trifluoromethyl)-2,4-Dibromobenzene
CAS No.	1805589-49-4
Molecular Formula	C8H2Br2F6
Molecular Weight	375.91 g/mol
Synonyms	2,4-Dibromo-1,3-bis(trifluoromethyl)benzene; 2,4-Dibromo-α,α,α,α',α',α'-hexafluoro-m-xylene; 1,3-Di(trifluoromethyl)-2,4-dibromobenzene; Benzene, 1,3-bis(trifluoromethyl)-2,4-dibromo-; m-Xylene, 2,4-dibromo-α,α,α,α',α',α'-hexafluoro-; 2,4-Dibromo-1,3-di(trifluoromethyl)benzene
EINECS	Contact for details

Quality Control

Our 1,3-Bis(Trifluoromethyl)-2,4-Dibromobenzene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot is analyzed using advanced techniques including HPLC, GC, NMR, and elemental analysis to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in a dark place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.