Description

1,3-Dibromo-5-Chloro-2-Fluorobenzene is a high-purity, multi-halogenated benzene derivative serving as a critical building block in advanced organic synthesis. Its unique halogen substitution pattern makes it an indispensable intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and material science industries who require precise and reliable halogenated intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting complex aromatic scaffolds.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where specific halogen patterns are required for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and electronic materials.
• Cross-Coupling Reactions: An excellent substrate for various palladium-catalyzed reactions (e.g., Suzuki, Stille, Negishi) due to the presence of bromine substituents.
• Organic Synthesis Research: A versatile reagent in academic and industrial R&D for exploring new synthetic methodologies and creating complex molecular architectures.
• Fluorine Chemistry: The fluorine atom provides a metabolically stable and lipophilic handle, making it valuable for developing compounds with improved pharmacokinetic properties.

Basic Information

Product Name	1,3-Dibromo-5-Chloro-2-Fluorobenzene
CAS No.	1805525-99-8
Molecular Formula	C6H2Br2ClF
Molecular Weight	292.34 g/mol
Synonyms	2-Fluoro-1,3-dibromo-5-chlorobenzene; 5-Chloro-1,3-dibromo-2-fluorobenzene; 1-Chloro-3,5-dibromo-2-fluorobenzene; Benzene, 1,3-dibromo-5-chloro-2-fluoro-; 1805525-99-8; 2-Fluoro-5-chloro-1,3-dibromobenzene; 1,3-Dibromo-5-chloro-2-fluorobenzol
EINECS	Contact for details

Quality Control

Our 1,3-Dibromo-5-Chloro-2-Fluorobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.