Description

5-Bromo-2-Fluoropyridin-4-Ol CAS NO 1805419-79-7 is a high-purity fluorinated pyridine derivative, a crucial building block in modern synthetic organic chemistry. Its unique halogenated structure makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and bromine substituents can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a building block for creating functionalized ligands, organic electronic materials, and liquid crystals.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to the presence of the bromine atom, enabling rapid diversification of molecular scaffolds.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and constructing compound libraries for screening.

Basic Information

Product Name	5-Bromo-2-Fluoropyridin-4-Ol
CAS No.	1805419-79-7
Molecular Formula	C5H3BrFNO
Molecular Weight	191.99 g/mol
Synonyms	4-Hydroxy-5-bromo-2-fluoropyridine; 5-Bromo-2-fluoro-4-hydroxypyridine; 5-Bromo-2-fluoropyridin-4-ol; 2-Fluoro-5-bromopyridin-4-ol; 5-Bromo-2-fluoro-4-pyridinol; 1805419-79-7
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2-Fluoropyridin-4-Ol is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We guarantee high chemical purity and consistency to meet the stringent requirements of advanced R&D and scale-up processes. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.