Description

Ethyl 5-Bromo-4-Fluoropicolinate is a high-purity, multi-functional chemical building block essential for advanced organic synthesis. This compound is valued for its unique halogenated picolinate structure, which enables precise molecular modifications in complex chemical pathways. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Serves as a crucial precursor in the creation of advanced herbicides, fungicides, and pesticides with enhanced efficacy.
• Ligand and Catalyst Development: Used in the design and synthesis of novel ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials and specialty polymers.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific halogenated heterocycles.

Basic Information

Product Name	Ethyl 5-Bromo-4-Fluoropicolinate
CAS No.	1805152-37-7
Molecular Formula	C8H7BrFNO2
Molecular Weight	248.05 g/mol
Synonyms	Ethyl 5-bromo-4-fluoropyridine-2-carboxylate; 5-Bromo-4-fluoropicolinic acid ethyl ester; 2-Pyridinecarboxylic acid, 5-bromo-4-fluoro-, ethyl ester; 4-Fluoro-5-bromopicolinic acid ethyl ester; Ethyl 4-fluoro-5-bromopicolinate; 1805152-37-7
EINECS	Contact for details

Quality Control

Our Ethyl 5-Bromo-4-Fluoropicolinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high standards, including cGMP development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.