Description

Benzene, 2-Bromo-1,3-Difluoro-5-Methyl- is a high-purity, multi-functional halogenated aromatic building block. This compound is valued for its unique substitution pattern, which provides distinct reactivity and electronic properties for advanced chemical synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring specific halogenated aromatic cores.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluoro and bromo substituents modulate biological activity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Buchwald-Hartwig amination, leveraging the reactive bromine atom.
• Fluorine Chemistry Research: A valuable reagent for studying the effects of fluorine atoms on aromatic systems in medicinal and materials chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for use in custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	Benzene, 2-Bromo-1,3-Difluoro-5-Methyl-
CAS No.	1805120-10-8
Molecular Formula	C7H5BrF2
Molecular Weight	207.02 g/mol
Synonyms	2-Bromo-1,3-difluoro-5-methylbenzene; 1-Bromo-2,4-difluoro-6-methylbenzene; 3-Bromo-2,6-difluorotoluene; 2,6-Difluoro-3-bromotoluene; 2-Bromo-α,α,α',α'-tetrafluoro-m-xylene (partial descriptor); Bromodifluoromethylbenzene isomer; BDFMB (abbrev.)
EINECS	Contact for details

Quality Control

Every batch of Benzene, 2-Bromo-1,3-Difluoro-5-Methyl- is produced and analyzed under strict quality management protocols. We ensure compliance with relevant industry standards for fine chemicals and advanced intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee reproducible performance in your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.