Description

5-Fluoro-2-Methylpyridine-4-Carbonitrile is a high-purity fluorinated pyridine derivative, a key heterocyclic building block in advanced organic synthesis. Its molecular structure, featuring both a fluorine substituent and a nitrile group, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers in the development of specialty polymers, liquid crystals, and electronic materials.
• Chemical Biology & Proteomics: Employed as a versatile scaffold for creating chemical probes and molecular tags used in drug discovery and biological pathway analysis.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring the introduction of a fluorinated pyridine core into target molecules.

Basic Information

Product Name	5-Fluoro-2-Methylpyridine-4-Carbonitrile
CAS No.	1805052-14-5
Molecular Formula	C7H5FN2
Molecular Weight	136.13 g/mol
Synonyms	4-Cyano-5-fluoro-2-methylpyridine; 2-Methyl-5-fluoropyridine-4-carbonitrile; 5-Fluoro-2-picolinonitrile; 5-Fluoro-2-methyl-4-pyridinecarbonitrile; 1805052-14-5; 5-Fluoro-2-methylisonicotinonitrile
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Methylpyridine-4-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.