Description

3-Bromo-6-(Difluoromethyl)Pyridin-2-Amine is a high-value, multi-functional pyridine derivative building block designed for advanced chemical synthesis. Its molecular structure, featuring both bromo and difluoromethyl substituents on an amine-functionalized pyridine core, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to introduce key pharmacophores and modulate the biological activity, metabolic stability, and physicochemical characteristics of target compounds.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors, antiviral agents, and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the difluoromethyl group can enhance bioavailability and environmental stability.
• Material Science Research: Employed in the development of advanced organic materials, such as ligands for catalysts, organic semiconductors, and liquid crystals.
• Chemical Biology & Proteomics: Acts as a versatile scaffold for creating molecular probes and tool compounds to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A pivotal starting material for custom synthesis projects requiring precise functionalization of the pyridine ring system.

Basic Information

Product Name	3-Bromo-6-(Difluoromethyl)Pyridin-2-Amine
CAS No.	1805028-09-4
Molecular Formula	C6H5BrF2N2
Molecular Weight	223.02 g/mol
Synonyms	2-Amino-3-bromo-6-(difluoromethyl)pyridine; 3-Bromo-6-(difluoromethyl)-2-pyridinamine; 2-Pyridinamine, 3-bromo-6-(difluoromethyl)-; 1805028-09-4; 3-Bromo-6-difluoromethyl-pyridin-2-ylamine; 6-(Difluoromethyl)-3-bromopyridin-2-amine
EINECS	Contact for details

Quality Control

Our 3-Bromo-6-(Difluoromethyl)Pyridin-2-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports applications requiring high-purity intermediates under cGMP and ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified for high-purity grades.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (HPLC)	≥98.0% / ≥99.0% (High Purity Grades)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.