Description

3-Bromo-2,4-Difluorobenzotrifluoride is a high-value, multi-functional fluorinated aromatic building block. This compound is engineered to serve as a critical intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), offering unique reactivity for selective cross-coupling and functionalization. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: Key synthon for the development of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutics.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides and pesticides, where the fluorine and bromine substituents contribute to biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Incorporated into specialty polymers to impart unique chemical resistance, thermal stability, and low surface energy properties.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Chemical Research & Development: A versatile reagent for exploring new synthetic pathways and creating novel fluorinated aromatic compounds in academic and industrial labs.

Basic Information

Product Name	3-Bromo-2,4-Difluorobenzotrifluoride
CAS No.	1805023-67-9
Molecular Formula	C7H2BrF5
Molecular Weight	260.99 g/mol
Synonyms	1-Bromo-2,4-difluoro-3-(trifluoromethyl)benzene; 2,4-Difluoro-3-(trifluoromethyl)bromobenzene; 3-Bromo-2,4-difluoro-α,α,α-trifluorotoluene; Benzene, 1-bromo-2,4-difluoro-3-(trifluoromethyl)-; 3-Bromo-2,4-difluoro(trifluoromethyl)benzene
EINECS	Contact for details

Quality Control

Our 3-Bromo-2,4-Difluorobenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is between 2°C and 25°C. Keep container tightly sealed when not in use to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.