Description

Ethyl 6-(Difluoromethyl)Picolinate is a high-purity, specialized organic compound featuring a difluoromethylated picolinate ester structure. This molecule serves as a critical advanced pharmaceutical intermediate and a versatile building block in modern synthetic chemistry. It is primarily utilized by R&D and production teams in the agrochemical and pharmaceutical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Serves as a crucial precursor for developing new-generation herbicides and fungicides with enhanced efficacy and environmental profiles.
• Chemical Research & Development: Used as a versatile fluorinated building block for constructing heterocyclic compounds and exploring structure-activity relationships (SAR).
• Material Science Precursor: Employed in the research of specialty polymers and liquid crystals where fluorine substitution imparts desired properties like chemical resistance and stability.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity fluorinated intermediates.

Basic Information

Product Name	Ethyl 6-(Difluoromethyl)Picolinate
CAS No.	1804934-02-8
Molecular Formula	C9H9F2NO2
Molecular Weight	201.17 g/mol
Synonyms	Ethyl 6-(difluoromethyl)pyridine-2-carboxylate; 2-Pyridinecarboxylic acid, 6-(difluoromethyl)-, ethyl ester; 6-(Difluoromethyl)picolinic acid ethyl ester; Ethyl 6-difluoromethylpicolinate; Ethyl 2-(difluoromethyl)pyridine-6-carboxylate
EINECS	Contact for details

Quality Control

Every batch of Ethyl 6-(Difluoromethyl)Picolinate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles where applicable for pharmaceutical-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.