Description

4-Amino-5-Fluoropicolinic Acid is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a critical intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its unique picolinic acid core and fluorine substitution offer valuable synthetic handles. It is primarily needed by research chemists and process development scientists working on active pharmaceutical ingredients (APIs), novel agrochemicals, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting enzymes or receptors where the picolinic acid scaffold is pharmacologically relevant.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of fluorinated heterocycles.
• Ligand Synthesis: Serves as a precursor for creating chelating ligands in coordination chemistry and catalysis.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes.
• Material Science Research: Potential monomer or additive in the development of specialized polymers and advanced materials.

Basic Information

Product Name	4-Amino-5-Fluoropicolinic Acid
CAS No.	1804052-68-3
Molecular Formula	C6H5FN2O2
Molecular Weight	156.12 g/mol
Synonyms	5-Fluoro-4-aminopicolinic acid; 4-Amino-5-fluoro-2-pyridinecarboxylic acid; 2-Pyridinecarboxylic acid, 4-amino-5-fluoro-; 5-Fluoro-4-aminopyridine-2-carboxylic acid; 4-Amino-5-fluoropyridine-2-carboxylic acid; 1804052-68-3; 4-Amino-5-fluoro-2-picolinic acid
EINECS	Contact for details

Quality Control

Our 4-Amino-5-Fluoropicolinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.