Description

3-Pyridinol, 4-(Difluoromethyl)- is a high-purity, fluorinated pyridine derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile building block for the development of novel active ingredients. It is primarily utilized by research institutions and industrial manufacturers in the agrochemical and pharmaceutical sectors for creating new molecules with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used as a building block for novel herbicides, fungicides, and insecticides, leveraging the difluoromethyl group to modulate bioavailability and stability.
• Ligand and Catalyst Development: Employed in organometallic chemistry for the synthesis of specialized ligands and catalysts used in cross-coupling and other catalytic reactions.
• Material Science Research: Acts as a precursor for functionalized polymers and advanced organic materials with specific electronic or surface properties.
• Fluorine Chemistry Studies: Serves as a model compound in academic and industrial research exploring the effects of fluorination on molecular reactivity and physicochemical characteristics.

Basic Information

Product Name	3-Pyridinol, 4-(Difluoromethyl)-
CAS No.	1803997-29-6
Molecular Formula	C6H5F2NO
Molecular Weight	145.11 g/mol
Synonyms	4-(Difluoromethyl)pyridin-3-ol; 4-(Difluoromethyl)-3-hydroxypyridine; 3-Hydroxy-4-(difluoromethyl)pyridine; 3-Pyridinol, 4-(difluoromethyl)-; 4-Difluoromethyl-3-pyridinol; 3-Hydroxy-4-difluoromethylpyridine; 4-(Difluoromethyl)-3-pyridinol
EINECS	Contact for details

Quality Control

Every batch of 3-Pyridinol, 4-(Difluoromethyl)- is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency. Our products are suitable for demanding R&D and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.