Description

Methyl 3-Fluoro-5-(Trifluoromethyl)Picolinate is a high-value fluorinated pyridine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its structure, featuring both fluorine and trifluoromethyl groups, is engineered to impart desirable properties such as metabolic stability and enhanced lipophilicity to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and insecticides, where the fluorine motifs contribute to improved biological activity and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of advanced organic electronic materials and liquid crystals due to its electron-withdrawing characteristics.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Item	Details
Product Name	Methyl 3-Fluoro-5-(Trifluoromethyl)Picolinate
CAS No.	1803834-87-8
Molecular Formula	C8H5F4NO2
Molecular Weight	223.12 g/mol
Synonyms	Methyl 3-Fluoro-5-(trifluoromethyl)pyridine-2-carboxylate; 2-Pyridinecarboxylic acid, 3-fluoro-5-(trifluoromethyl)-, methyl ester; 3-Fluoro-5-(trifluoromethyl)picolinic acid methyl ester; Methyl 3-fluoro-5-(trifluoromethyl)picolinate; Methyl 3-fluoro-5-trifluoromethylpicolinate
EINECS	Contact for details

Quality Control

Every batch of Methyl 3-Fluoro-5-(Trifluoromethyl)Picolinate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and batch-to-batch consistency essential for sensitive R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.