Description

3-Fluoro-6-Iodo-2-Nitrotoluene is a high-purity, multi-functional halogenated aromatic building block essential for advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecular architectures in pharmaceutical and agrochemical research. This compound is primarily utilized by R&D chemists and process development scientists in the fine chemical and life sciences industries to introduce fluorine, iodine, and nitro functional groups into target molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of novel fluorinated drug candidates.
• Agrochemical Research: Used in creating advanced herbicides, fungicides, and insecticides where halogenated aromatic rings enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Negishi couplings for carbon-carbon bond formation.
• Fluorine Chemistry Studies: An important reagent for investigating the effects of fluorine substitution on molecular properties such as bioavailability, lipophilicity, and metabolic stability.
• Dye and Pigment Synthesis: Intermediate in the production of complex, halogenated dyes and pigments for high-performance applications.

Basic Information

Product Name	3-Fluoro-6-Iodo-2-Nitrotoluene
CAS No.	1803766-15-5
Molecular Formula	C7H5FINO2
Molecular Weight	281.03 g/mol
Synonyms	1-Fluoro-2-methyl-3-iodo-6-nitrobenzene; 2-Methyl-3-fluoro-6-iodonitrobenzene; 3-Fluoro-2-methyl-1-iodo-4-nitrobenzene; 2-Nitro-3-fluoro-6-iodotoluene; Toluene, 3-fluoro-6-iodo-2-nitro-; 6-Iodo-3-fluoro-2-nitrotoluene
EINECS	Contact for details

Quality Control

Our 3-Fluoro-6-Iodo-2-Nitrotoluene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.