Description

6-Bromo-2-Fluoropyridine-3-Carbonitrile is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its unique halogenated pyridine core, which enables precise molecular modifications in complex chemical architectures. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a building block for creating functionalized ligands, organic semiconductors, and advanced polymers.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects and library generation.

Basic Information

Product Name	6-Bromo-2-Fluoropyridine-3-Carbonitrile
CAS No.	1802889-85-5
Molecular Formula	C6H2BrFN2
Molecular Weight	200.99 g/mol
Synonyms	2-Fluoro-6-bromopyridine-3-carbonitrile; 3-Cyano-6-bromo-2-fluoropyridine; 6-Bromo-2-fluoro-3-cyanopyridine; 2-Fluoro-6-bromo-3-pyridinecarbonitrile; 1802889-85-5; 6-Bromo-2-fluoronicotinonitrile
EINECS	Contact for details

Quality Control

Every batch of 6-Bromo-2-Fluoropyridine-3-Carbonitrile is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC-MS, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.